Cep164, but not EB1, is critical for centriolar localization of TTBK2 and its function in ciliogenesis

@inproceedings{Oda2015Cep164BN,
  title={Cep164, but not EB1, is critical for centriolar localization of TTBK2 and its function in ciliogenesis},
  author={Toshiaki Oda and Shuhei Chiba and Tomoaki Nagai and Kensaku Mizuno},
  booktitle={Cilia},
  year={2015}
}
Objective Primary cilia play crucial roles in sensing and transducing external signals. They extend the axoneme from the mother centriole-derived basal body. A centrosomal protein CP110 blocks axoneme extension and is removed from the mother centriole at the onset of ciliogenesis. TTBK2 is recruited to the mother centriole in response to serum starvation and is required for CP110 removal and ciliogenesis. To elucidate the mechanism of centriolar recruitment of TTBK2, we examined the roles of… CONTINUE READING
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