Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB.

@article{Koyanagi2005CentrosomalPP,
  title={Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB.},
  author={Michiyo Koyanagi and Makoto Hijikata and Koichi Watashi and Osamu Masui and Kunitada Shimotohno},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 13},
  pages={12430-7}
}
Nuclear factor-kappaB (NF-kappaB) is a transcription factor important for various cellular events such as inflammation, immune response, proliferation, and apoptosis. In this study, we performed a yeast two-hybrid screening using the N-terminal domain of the p65 subunit (RelA) of NF-kappaB as bait and isolated centrosomal P4.1-associated protein (CPAP) as a candidate for a RelA-associating partner. Glutathione S-transferase pull-down assays and co-immunoprecipitation experiments followed by… CONTINUE READING

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