Centromeric Cohesion Is Protected Twice at Meiosis, by SHUGOSHINs at Anaphase I and by PATRONUS at Interkinesis

@article{Cromer2013CentromericCI,
  title={Centromeric Cohesion Is Protected Twice at Meiosis, by SHUGOSHINs at Anaphase I and by PATRONUS at Interkinesis},
  author={Laurence Cromer and Sylvie Jolivet and Christine Horlow and Liudmila Chelysheva and Jefri Heyman and Geert De Jaeger and Csaba Koncz and Lieven de Veylder and Rapha{\"e}l Mercier},
  journal={Current Biology},
  year={2013},
  volume={23},
  pages={2090-2099}
}
BACKGROUND At meiosis, two successive rounds of chromosome segregation lead to ploidy halving. This is achieved through a stepwise release of sister chromatid cohesion, along chromosome arms to allow homolog segregation at anaphase I and at centromeres to allow sister chromatid segregation at anaphase II. Cohesins, the protein complex that ensures cohesion… CONTINUE READING