Centromeres put epigenetics in the driver's seat.

  title={Centromeres put epigenetics in the driver's seat.},
  author={R. Kelly Dawe and Steven Henikoff},
  journal={Trends in biochemical sciences},
  volume={31 12},
A defining feature of chromosomes is the centromere, the site for spindle attachment at mitosis and meiosis. Intriguingly, centromeres of plants and animals are maintained by both sequence-specific and sequence-independent (epigenetic) processes. Epigenetic inheritance might enable kinetochores (the structures that attach centromeres to spindles) to maintain an optimal size. However, centromeres are susceptible to the evolution of "selfish" DNA repeats that bind to kinetochore proteins. We… CONTINUE READING


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Female drive

  • J. Puechberty
  • Genes in Conflict : The Biology of Selfish…
  • 2006

Female drive. In Genes in Conflict: The Biology of Selfish Genetic Elements

  • A. Burt, R. Strivers
  • 2006

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