Centromere identity: a challenge to be faced

@article{Mehta2010CentromereIA,
  title={Centromere identity: a challenge to be faced},
  author={Gunjan Mehta and Meenakshi Agarwal and Santanu K. Ghosh},
  journal={Molecular Genetics and Genomics},
  year={2010},
  volume={284},
  pages={75-94}
}
The centromere is a genetic locus, required for faithful chromosome segregation, where spindle fibers attach to the chromosome through kinetochore. Loss of centromere or formation of multiple centromeres on a single chromosome leads to chromosome missegregation or chromosome breakage, respectively, which are detrimental for fitness and survival of a cell. Therefore, understanding the mechanism of centromere locus determination on the chromosome and perpetuation of such a locus in subsequent… 
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