Centrolobular liver fibrosis in the hypercholesterolemic rabbit.


During a study on the development of atheromatous lesions in rabbits fed a diet with a low or high cholesterol supplement, we found a moderate to pronounced centrolobular liver fibrosis. This fibrosis developed in three stages. Early after supplementation of cholesterol, we observed increased immunoreactivity of collagen types I, III, and IV, and… (More)


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@article{Buyssens1996CentrolobularLF, title={Centrolobular liver fibrosis in the hypercholesterolemic rabbit.}, author={Norbert Buyssens and Marc M. Kockx and Anna Herman and James Lazou and Klaske van den Berg and Eddie Wisse and Andreas Geerts}, journal={Hepatology}, year={1996}, volume={24 4}, pages={939-46} }