Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin.

@article{Nagasao2003CentroacinarAI,
  title={Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin.},
  author={Jun Nagasao and Kazuki Yoshioka and Hajime Amasaki and Ken-ichiro Mutoh},
  journal={Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft},
  year={2003},
  volume={185 3},
  pages={
          211-6
        }
}
The present study examined the possibility for regeneration of pancreatic endocrine cells from centroacinar (CA) and intercalated duct (ICD) cells in rat pancreas after 5 days of continuous streptozotocin (STZ) administration. Nine rats were divided into 3 experimental groups: 1) Control group, 2) Short term recovery group; three days after STZ administration (STZ 3), and 3) Long term recovery group; ten days post-STZ administration (STZ 10). The CA and ICD cells in the STZ 3 group had swollen… CONTINUE READING
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