Centriole assembly in Caenorhabditis elegans

@article{Pelletier2006CentrioleAI,
  title={Centriole assembly in Caenorhabditis elegans},
  author={Laurence Pelletier and Eileen T. O’Toole and Anne Schwager and Anthony A. Hyman and Thomas M{\"u}ller-Reichert},
  journal={Nature},
  year={2006},
  volume={444},
  pages={619-623}
}
Centrioles are necessary for flagella and cilia formation, cytokinesis, cell-cycle control and centrosome organization/spindle assembly. They duplicate once per cell cycle, but the mechanisms underlying their duplication remain unclear. Here we show using electron tomography of staged C. elegans one-cell embryos that daughter centriole assembly begins with the formation and elongation of a central tube followed by the peripheral assembly of nine singlet microtubules. Tube formation and… CONTINUE READING
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