Centriole assembly in Caenorhabditis elegans

  title={Centriole assembly in Caenorhabditis elegans},
  author={Laurence Pelletier and Eileen T. O’Toole and Anne Schwager and Anthony A. Hyman and Thomas M{\"u}ller-Reichert},
Centrioles are necessary for flagella and cilia formation, cytokinesis, cell-cycle control and centrosome organization/spindle assembly. They duplicate once per cell cycle, but the mechanisms underlying their duplication remain unclear. Here we show using electron tomography of staged C. elegans one-cell embryos that daughter centriole assembly begins with the formation and elongation of a central tube followed by the peripheral assembly of nine singlet microtubules. Tube formation and… CONTINUE READING
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