Centriole assembly and the role of Mps1: defensible or dispensable?

@inproceedings{Pike2011CentrioleAA,
  title={Centriole assembly and the role of Mps1: defensible or dispensable?},
  author={Amanda N Pike and Harold A. Fisk},
  booktitle={Cell Division},
  year={2011}
}
The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C. elegans being a notable exception, and has also been shown to regulate the spindle checkpoint and an increasing number of cellular functions relating to genomic stability. While its function in the spindle checkpoint appears to be both universally conserved and… CONTINUE READING

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