Centrin-mediated microtubule severing during flagellar excision in Chlamydomonas reinhardtii

@article{Sanders1989CentrinmediatedMS,
  title={Centrin-mediated microtubule severing during flagellar excision in Chlamydomonas reinhardtii},
  author={Mark A. Sanders and Jeffery L. Salisbury},
  journal={The Journal of Cell Biology},
  year={1989},
  volume={108},
  pages={1751 - 1760}
}
Chlamydomonas cells excise their flagella in response to a variety of experimental conditions (e.g., extremes of temperature or pH, alcohol or detergent treatment, and mechanical shear). Here, we show that flagellar excision is an active process whereby microtubules are severed at select sites within the transition zone. The transition zone is located between the flagellar axoneme and the basal body; it is characterized by a pair of central cylinders that have an H shape when viewed in… CONTINUE READING