Centrally administered opioid antagonists, nor-binaltorphimine, 16-methyl cyprenorphine and MR2266, suppress intake of a sweet solution

@article{Calcagnetti1990CentrallyAO,
  title={Centrally administered opioid antagonists, nor-binaltorphimine, 16-methyl cyprenorphine and MR2266, suppress intake of a sweet solution},
  author={Daniel J. Calcagnetti and Robin Lynn Calcagnetti and Michael S. Fanselow},
  journal={Pharmacology Biochemistry and Behavior},
  year={1990},
  volume={35},
  pages={69-73}
}
36 Citations
The kappa-opioid U-50,488H suppresses the initiation of nocturnal spontaneous drinking in normally hydrated rats
TLDR
It is suggested that kappa-receptors play a pivotal role in modulating spontaneous drinking in the normally hydrated rat and that this control is mainly exerted on the motivational aspect of drinking.
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References

SHOWING 1-10 OF 30 REFERENCES
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.
TLDR
Nor-BNI and U-50,488H were used to demonstrate that kappa opioid receptors in the spinal cord were more important than those located supraspinally for kappa-mediated analgesia and the comparatively low selectivity of BNI in receptor binding studies did not correlate with the high pharmacologic selectivity for k Kappa receptors.
Role of mu and kappa opioid receptors in conditional fear-induced analgesia: the antagonistic actions of nor-binaltorphimine and the cyclic somatostatin octapeptide, Cys2Tyr3Orn5Pen7-amide.
TLDR
It appears that mu and delta, but not kappa receptors, are involved in this opioid form of stress-induced analgesia.
Endogenous opioid peptides and regulation of drinking and feeding.
  • L. D. Reid
  • Biology, Psychology
    The American journal of clinical nutrition
  • 1985
TLDR
A conclusion that opioid peptides are part of a system for regulating ingestion is supported to support a conclusion that Benzodiazepines enhance drinking and eating and apparently interact with opioid systems.
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