Centrally administered neurotensin suppresses locomotor hyperactivity induced by d-amphetamine but not by scopolamine or caffeine.

@article{Skoog1986CentrallyAN,
  title={Centrally administered neurotensin suppresses locomotor hyperactivity induced by d-amphetamine but not by scopolamine or caffeine.},
  author={K M Skoog and Scott T. Cain and Charles B. Nemeroff},
  journal={Neuropharmacology},
  year={1986},
  volume={25 7},
  pages={777-82}
}
The effects of intracisternally (i.c.) administered neurotensin (NT) on locomotor responses to scopolamine and caffeine, two psychomotor stimulants which do not depend on an intact mesolimbic dopamine (DA) system, were compared with the effects of the peptide on locomotion induced by d-amphetamine, which does depend on this DA system. Adult rats were… CONTINUE READING