Centrally administered insulin potentiates the pressor response to angiotensin II.

Abstract

The aim of the present study was to determine if insulin can modulate the pressor response to angiotensin II at brain level in normotensive rats. Anaesthetized male rats were intracerebroventricularly infused with insulin (12 mU/h, n=15) or Ringer's solution as vehicle (n=15) for 2 h. Immediately, changes in mean arterial pressure (MAP) in response to an… (More)
DOI: 10.1016/j.regpep.2010.04.001

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