Central versus Peripheral Tumor Location: Influence on Survival, Local Control, and Toxicity Following Stereotactic Body Radiotherapy for Primary Non-Small-Cell Lung Cancer.

@article{Park2015CentralVP,
  title={Central versus Peripheral Tumor Location: Influence on Survival, Local Control, and Toxicity Following Stereotactic Body Radiotherapy for Primary Non-Small-Cell Lung Cancer.},
  author={Henry S Park and Eileen M Harder and Brandon R Mancini and Roy H. Decker},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2015},
  volume={10 5},
  pages={832-7}
}
INTRODUCTION Stereotactic body radiotherapy (SBRT) has been increasingly utilized for medically inoperable early stage non-small-cell lung cancer. However, a lower biological equivalent dose (BED) is often used for central tumors given toxicity concerns, potentially leading to decreased local control (LC). We compared survival, LC, and toxicity outcomes for SBRT patients with centrally versus peripherally located tumors. METHODS We included patients with primary cT1-2N0M0 non-small-cell lung… CONTINUE READING
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