Central venous pressure measurements improve the accuracy of leg raising-induced change in pulse pressure to predict fluid responsiveness

@article{Lakhal2010CentralVP,
  title={Central venous pressure measurements improve the accuracy of leg raising-induced change in pulse pressure to predict fluid responsiveness},
  author={Karim Lakhal and Stephan Ehrmann and Isabelle Runge and Dalila Benzekri-Lef{\`e}vre and Annick Legras and Pierre François Dequin and Emmanuelle Mercier and Michel Wolff and Bernard R{\'e}gnier and Thierry Boulain},
  journal={Intensive Care Medicine},
  year={2010},
  volume={36},
  pages={940-948}
}
Passive leg raising (PLR) is a maneuver performed to test the cardiac Frank-Starling mechanism. We assessed the influence of PLR-induced changes in preload on the performance of PLR-induced change in pulse pressure (ΔPLRPP) and cardiac output (ΔPLRCO) for fluid responsiveness prediction. Sedated, nonarrhythmic patients with persistent shock were included in this prospective multicenter study. Cardiac output and pulse pressure were measured at baseline (patient supine), during PLR (lower limbs… CONTINUE READING

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