Central venous-arterial carbon dioxide difference as an indicator of cardiac index

  title={Central venous-arterial carbon dioxide difference as an indicator of cardiac index},
  author={Joseph Cuschieri and Emanuel P. Rivers and Michael W. Donnino and Marius Katilius and Gordon R Jacobsen and H. Bryant Nguyen and Nikolai Pamukov and H. Mathilda Horst},
  journal={Intensive Care Medicine},
Abstract Objective: The mixed venous-arterial (v-a) pCO2 difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO2, which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial pCO2 difference and CI. Design: Prospective, cohort study. Setting: Intensive care unit of an urban tertiary care hospital. Patients and participants: Eighty-three consecutive… 
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Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock.
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The likelihood of a bad outcome seems to be enhanced when a high pCO2 gap persists after 24 h of therapy, and the clinical utility of central venous p CO2 values is of potential interest in determining the venous-arterial pCO1 difference.
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Do fluctuations of PaCO2 impact on the venous-arterial carbon dioxide gradient?
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P(a-v)CO2 represents a useful even if aspecific parameter to monitor patients during the early postoperative period after myocardial revascularization, and was influenced by the metabolic rate, the body temperature, and the impaired CO2 elimination through the lungs.
Comparison of central-venous to mixed-venous oxygen saturation during changes in oxygen supply/demand.
Although absolute values of ScvO2 are not sufficiently identical to SvO2 to calculate O2 uptake or pulmonary shunt precisely, close tracking of changes in the two sites across a wide range of hemodynamic conditions warrant further consideration of ScVO2 for patient monitoring of trends in O2 supply/demand.
Veno-arterial carbon dioxide gradient in human septic shock.
dPCO2 patients with septic shock is related principally to cardiac output but apparently also to the degree of pulmonary impairment, and although dPCO 2 is larger in nonsurvivors, its prognostic value is modest.
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The ΔPCO2/C(a-v)O2 ratio seems a reliable marker of global anaerobic metabolism and would be helpful for a better interpretation of pulmonary artery catheter data.
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Since its introduction into clinical practice by Swan and colleagues in 1970, pulmonary artery catheterization has remained the ‘gold standard’ of hemodynamic monitoring for the critically ill
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