Central serotonergic responsiveness in neurocardiogenic syncope: a clomipramine test challenge.

@article{Theodorakis1998CentralSR,
  title={Central serotonergic responsiveness in neurocardiogenic syncope: a clomipramine test challenge.},
  author={George Theodorakis and Manolis Markianos and Efthimios G Livanis and Elias Zarvalis and Panagiota G Flevari and Dimitri Th Kremastinos},
  journal={Circulation},
  year={1998},
  volume={98 24},
  pages={2724-30}
}
BACKGROUND Central serotonergic mechanisms appear to participate in the pathogenesis of recurrent neurally mediated syncope. The aim of the study was to investigate the responsiveness of the central serotonergic system by measuring the prolactin and cortisol responses to intravenous administration of the serotonin reuptake inhibitor clomipramine. METHODS AND RESULTS Twenty subjects free of any medical treatment were tested. Twelve had a history of recurrent syncopal attacks and positive tilt… CONTINUE READING

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