Central role of soluble adenylyl cyclase and cAMP in sperm physiology.

@article{Buffone2014CentralRO,
  title={Central role of soluble adenylyl cyclase and cAMP in sperm physiology.},
  author={Mariano Gabriel Buffone and Eva V Wertheimer and Pablo E Visconti and Dar{\'i}o Krapf},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1842 12 Pt B},
  pages={2610-20}
}
Cyclic adenosine 3',5'-monophosphate (cAMP), the first second messenger to be described, plays a central role in cell signaling in a wide variety of cell types. Over the last decades, a wide body of literature addressed the different roles of cAMP in cell physiology, mainly in response to neurotransmitters and hormones. cAMP is synthesized by a wide variety of adenylyl cyclases that can generally be grouped in two types: transmembrane adenylyl cyclase and soluble adenylyl cyclases. In… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 206 references

Tomes, Calcium-induced acrosomal exocytosis requires CAMP acting through a protein kinase A-independent, Epac-mediated pathway

  • M. T. Branham, C.N.L.S. Mayorga
  • J. Biol. Chem
  • 2006
Highly Influential
4 Excerpts

Graybiel, A family of CAMP-binding proteins that directly activate

  • H. Kawasaki, G. M. Springett, +4 authors A.M.D.E. Housman
  • Rap1, Science
  • 1998
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…