Central release of nitric oxide mediates antinociception induced by aerobic exercise


Nitric oxide (NO) is a soluble gas that participates in important functions of the central nervous system, such as cognitive function, maintenance of synaptic plasticity for the control of sleep, appetite, body temperature, neurosecretion, and antinociception. Furthermore, during exercise large amounts of NO are released that contribute to maintaining body… (More)
DOI: 10.1590/1414-431X20144160


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