Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains.

@article{Slawson2011CentralRO,
  title={Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains.},
  author={Justin B. Slawson and Elena A. Kuklin and Aki Ejima and Konark Mukherjee and L. B. Ostrovsky and Leslie C. Griffith},
  journal={Genetics},
  year={2011},
  volume={187 1},
  pages={171-84}
}
Genetic causes for disturbances of locomotor behavior can be due to muscle, peripheral neuron, or central nervous system pathologies. The Drosophila melanogaster homolog of human CASK (also known as caki or camguk) is a molecular scaffold that has been postulated to have roles in both locomotion and plasticity. These conclusions are based on studies using overlapping deficiencies that largely eliminate the entire CASK locus, but contain additional chromosomal aberrations as well. More… CONTINUE READING

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