Central regulation of feeding behavior during social isolation of rat: evidence for the role of endogenous CART system

@article{Nakhate2011CentralRO,
  title={Central regulation of feeding behavior during social isolation of rat: evidence for the role of endogenous CART system},
  author={Kartik T. Nakhate and Dadasaheb M Kokare and P S Singru and Nishikant K. Subhedar},
  journal={International Journal of Obesity},
  year={2011},
  volume={35},
  pages={773-784}
}
Objective:Although hyperphagia and body weight gain are well-recognized consequences of social isolation, the underlying mechanisms are not understood. The aim of this work is to test the possibility that the endogenous cocaine- and amphetamine-regulated transcript peptide (CART) may be involved in the process.Design:Socially isolated rats were screened for increase in food intake and body weight, and the modifications of these parameters by CART were evaluated. Furthermore, isolated animals… CONTINUE READING