Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions.

Abstract

TRH is a tripeptide amide that functions as a neurotransmitter but also serves as a neurohormone that has a critical role in the central regulation of the hypothalamic-pituitary-thyroid axis. Hypophysiotropic TRH neurons involved in this neuroendocrine process are located in the hypothalamic paraventricular nucleus and secrete TRH into the pericapillary… (More)
DOI: 10.1210/er.2013-1087

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