Central region-of-interest analysis of lumbar spine densitometry demonstrates lower bone mass in older rhesus monkeys.

@article{Krueger1999CentralRA,
  title={Central region-of-interest analysis of lumbar spine densitometry demonstrates lower bone mass in older rhesus monkeys.},
  author={Diane C. Krueger and Heather Todd and A L Haffa and Janet Bruner and Don Yandow and N Binkley},
  journal={Bone},
  year={1999},
  volume={24 1},
  pages={29-33}
}
Osteoarthritis (OA) spuriously elevates spine bone mineral density (BMD) as measured by dual-energy X-ray absorptiometry (DXA). This study documents spinal OA prevalence in adult female rhesus monkeys, and evaluates a custom central region-of-interest (CROI) analysis technique designed to minimize OA effects on BMD measurement. Lumbar spine radiographs were obtained on 71 animals, age 10-37 years. OA degree was blindly scored as none, minimal, or moderate/severe. Moderate/severe OA was not… CONTINUE READING