Central projections of intrinsically photosensitive retinal ganglion cells in the macaque monkey.

@article{Hannibal2014CentralPO,
  title={Central projections of intrinsically photosensitive retinal ganglion cells in the macaque monkey.},
  author={Jens Hannibal and Laxmikanth Kankipati and Christianne E. Strang and B. B. Peterson and Dennis M. Dacey and Paul D. R. Gamlin},
  journal={The Journal of comparative neurology},
  year={2014},
  volume={522 10},
  pages={2231-48}
}
Circadian rhythms generated by the suprachiasmatic nucleus (SCN) are entrained to the environmental light/dark cycle via intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin and the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP). The ipRGCs regulate other nonimage-forming visual functions such as the pupillary light reflex, masking behavior, and light-induced melatonin suppression. To evaluate whether PACAP-immunoreactive… CONTINUE READING