Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine.

@article{Leijon1989CentralPP,
  title={Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine.},
  author={G{\"o}ran S Leijon and J{\"o}rgen Boivie},
  journal={Pain},
  year={1989},
  volume={36 1},
  pages={27-36}
}
A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression. Treatment was given, in randomized order, for periods of 4 weeks, separated by 1 week wash-out. The final doses were 75 and 800 mg/day, respectively, for amitriptyline and carbamazepine. The treatment effects were assessed by daily ratings of pain intensity on a 10-step… CONTINUE READING

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