Central pair apparatus enhances outer-arm dynein activities through regulation of inner-arm dyneins.

@article{Kikushima2009CentralPA,
  title={Central pair apparatus enhances outer-arm dynein activities through regulation of inner-arm dyneins.},
  author={Kenji Kikushima},
  journal={Cell motility and the cytoskeleton},
  year={2009},
  volume={66 5},
  pages={272-80}
}
The beating of eukaryotic cilia and flagella is controlled by multiple species of inner-arm and outer-arm dyneins. To clarify the regulation on axonemal beating by nucleotide conditions and central-pair microtubules, microtubule sliding in disintegrating Chlamydomonas axonemes of various mutants and in vitro microtubule gliding by isolated axonemal dyneins were examined. In the in vitro motility assays with outer-arm dyneins (alphabeta and gamma), microtubule translocation velocity decreased at… CONTINUE READING
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