Central oxytocin mediates stress-induced tachycardia.

  title={Central oxytocin mediates stress-induced tachycardia.},
  author={Mariana Morris and Michael F. Callahan and Ping Li and Aldo Bolten Lucion},
  journal={Journal of neuroendocrinology},
  volume={7 6},
To address the role of oxytocin in the control of cardiovascular reactivity, we examined the effect of central injection of oxytocin, vasopressin and mixed base antisense oligodeoxynucleotides on stress-induced cardiovascular and endocrine changes. Antisense oligomers were injected into the paraventricular nucleus (PVN), 4 h prior to the stress test. The oxytocin antisense abolished the tachycardia produced by 5 min of shaker stress. The blood pressure and plasma oxytocin responses were not… CONTINUE READING


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