Central osteosclerosis with ectodermal dysplasia: clinical, laboratory, radiologic, and histopathologic characterization with review of the literature.

@article{Civitelli1989CentralOW,
  title={Central osteosclerosis with ectodermal dysplasia: clinical, laboratory, radiologic, and histopathologic characterization with review of the literature.},
  author={Roberto Civitelli and W Howard Mcalister and Steven L Teitelbaum and Michael P Whyte},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1989},
  volume={4 6},
  pages={863-75}
}
IBIDS is a syndrome characterized by ichthyosis, brittle hair, impaired intelligence, decreased fertility, and short stature, but unassociated with skeletal lesions. This condition is considered a form of trichothiodystrophy because hair from several cases has been found to have a low sulfur content. We describe a 9-year and 10-month-old white boy whose clinical features resemble the IBIDS syndrome (ichthyosis, brittle hair, cataracts, and short stature), but who also has marked axial… CONTINUE READING