Central neuropeptide Y induces proximal stomach relaxation via Y1 receptors in the dorsal vagal complex of the rat.

@article{Kobashi2006CentralNY,
  title={Central neuropeptide Y induces proximal stomach relaxation via Y1 receptors in the dorsal vagal complex of the rat.},
  author={Motoi Kobashi and Yuichi Shimatani and Keisuke Shirota and Song-Yu Xuan and Yoshihiro Mitoh and Ryuji Matsuo},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2006},
  volume={290 2},
  pages={R290-7}
}
Effects of neuropeptide Y (NPY) on motility of the proximal stomach was examined in anesthetized rats. Intragastric pressure was measured using a balloon situated in the proximal part of the stomach. Administration of NPY into the fourth ventricle induced relaxation of the proximal stomach in a dose-dependent manner. Administration of an Y1 receptor (Y1R) agonist [Leu31, Pro34]NPY induced a larger relaxation than NPY. The administration of an Y2 receptor agonist (NPY 13-36) did not induce… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 52 references

Centrally administered neuropeptide Y delays gastric emptying via Y2 receptors in rats.

American journal of physiology. Regulatory, integrative and comparative physiology • 2001
View 6 Excerpts
Highly Influenced

PYY and NPY: control of gastric motility via action on Y1 and Y2 receptors in the DVC.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 1997
View 12 Excerpts
Highly Influenced

Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.

Proceedings of the National Academy of Sciences of the United States of America • 1991
View 5 Excerpts
Highly Influenced

Neuropeptide Y (NPY) Y1 receptor mRNA is upregulated in association with R296 NPY INDUCES PROXIMAL STOMACH RELAXATION VIA Y1 RECEPTOR AJP-Regul

PS Kalra, MG Dube, B Xu, WG Farmerie, SP. Kalra
Integr Comp Physiol • 2006
View 1 Excerpt

Pathophysiology and treatment of functional dyspepsia.

Journal of clinical gastroenterology • 2005
View 1 Excerpt

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