Central nervous system toxicity associated with liposomal amphotericin B therapy for cutaneous leishmaniasis.

@article{Glasser2011CentralNS,
  title={Central nervous system toxicity associated with liposomal amphotericin B therapy for cutaneous leishmaniasis.},
  author={Jessie S Glasser and Clinton K. Murray},
  journal={The American journal of tropical medicine and hygiene},
  year={2011},
  volume={84 4},
  pages={566-8}
}
AmBisome (liposomal amphotericin B) is used for prophylaxis and treatment of fungal infections, treatment of visceral leishmaniasis, and more recently, treatment of cutaneous leishmaniasis. Although the package insert cites neurologic toxicities in up to 20% of cases, review of the literature did not reveal any specific cases describing this side effect, particularly in a patient without comorbidities. We describe a healthy 38-year-old male treated with liposomal amphotericin B for cutaneous… CONTINUE READING