Central nervous system reorganization in a variety of chronic pain states: a review.

  title={Central nervous system reorganization in a variety of chronic pain states: a review.},
  author={Douglas E Henry and Anthony E. Chiodo and Weibin Yang},
  journal={PM & R : the journal of injury, function, and rehabilitation},
  volume={3 12},
Chronic pain can develop from numerous conditions and is one of the most widespread and disabling health problems today. Unfortunately, the pathophysiology of chronic pain in most of these conditions, along with consistently effective treatments, remain elusive. However, recent advances in neuroimaging and neurophysiology are rapidly expanding our understanding of these pain syndromes. It is now clear that substantial functional and structural changes, or plasticity, in the central nervous… CONTINUE READING
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