Central nervous system metastases in HER-2-overexpressing metastatic breast cancer: a treatment challenge.

@article{Stemmler2008CentralNS,
  title={Central nervous system metastases in HER-2-overexpressing metastatic breast cancer: a treatment challenge.},
  author={Herbert Stemmler and Volker Heinemann},
  journal={The oncologist},
  year={2008},
  volume={13 7},
  pages={
          739-50
        }
}
With improvements in diagnostic and therapeutic options and a corresponding improvement in survival, central nervous system (CNS) metastasis is becoming a more frequent diagnosis in breast cancer patients. It can be assumed that up to 30% of metastatic breast cancer (MBC) patients may experience CNS metastasis during the course of their disease. Moreover, it has been reported that patients with human epidermal growth factor receptor (HER)-2-overexpressing MBC are at a higher risk for CNS… CONTINUE READING

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