Central nervous system mechanisms of analgesia

@article{Mayer1976CentralNS,
  title={Central nervous system mechanisms of analgesia},
  author={D. Mayer and Donald D. Price},
  journal={Pain},
  year={1976},
  volume={2},
  pages={379-404}
}
It has long been recognized that there are central nervous system mechanisms that can strikingly alter the perception of noxious stimuli. Indeed, recent theoretical treatments of pain have often given explicit recognition to this notion although little physiological detail has been available to support it [76,78,83]. The intent of this review is to examine and synthesize the extensive progress that has been made in the last few years describing the anatomical, physiological and neurohumoral… CONTINUE READING

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