Central nervous system immunity in mice infected with theiler's virus. I. Local neutralizing antibody response.

@article{Lipton1978CentralNS,
  title={Central nervous system immunity in mice infected with theiler's virus. I. Local neutralizing antibody response.},
  author={Howard L. Lipton and Francisco Gonz{\'a}lez-Scarano},
  journal={The Journal of infectious diseases},
  year={1978},
  volume={137 2},
  pages={145-51}
}
Experimental Theiler's mouse encephalomyelitis virus (TMEV) infection in mice is atypical of most other picornavirus infections because virus persists in the host. It was shown previously that low levels of infectious virus are readily detectable in the central nervous system (CNS) despite the presence of substantial titers of serum neutralizing antibody. In this study antibody assays were performed on CNS tissue homogenates, and neutralizing antibody was regularly found in the CNS of TMEV… CONTINUE READING

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