Central nervous system immune reconstitution disease in acquired immunodeficiency syndrome patients receiving highly active antiretroviral treatment.

@article{Gray2005CentralNS,
  title={Central nervous system immune reconstitution disease in acquired immunodeficiency syndrome patients receiving highly active antiretroviral treatment.},
  author={Françoise Gray and C{\'e}line Bazille and Homa Adle-Biassette and Jacqueline Mikol and Antoine Moulignier and Francesco Scaravilli},
  journal={Journal of neurovirology},
  year={2005},
  volume={11 Suppl 3},
  pages={16-22}
}
Highly active antiretroviral therapy (HAART)-induced immune restoration has been very beneficial for acquired immunodeficiency syndrome (AIDS) patients. In rare instances, HAART may induce a paradoxical clinical deterioration due to an immune reconstitution inflammatory syndrome (IRIS). This syndrome has been described with a wide variety of systemic infections and, in the central nervous system, with Cryptococcus neoformans infection, cytomegalovirus retinitis, and progressive multifocal… CONTINUE READING

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