Central nervous system effects of the crude extract of Erythrina velutina on rodents.

@article{Dantas2004CentralNS,
  title={Central nervous system effects of the crude extract of Erythrina velutina on rodents.},
  author={Marta Cl{\'e}a Costa Dantas and Fabio Santos de Oliveira and Simone Miranda Carozzi Bandeira and Josemar S. Batista and Clarence W. de Silva and P{\'e}ricles Barreto Alves and Angelo Roberto Antoniolli and Murilo Marchioro},
  journal={Journal of ethnopharmacology},
  year={2004},
  volume={94 1},
  pages={
          129-33
        }
}
The aqueous extract (AE) of Erythrina velutina prolonged the sleep duration induced by sodium pentobarbital (control: 6.4 +/- 1.2 min; extract 10 mg/kg, 47.1 +/- 3.9 min; extract 100 mg/kg, 109.4 +/- 7.2 min; F = 243, P < 0.001). In the open field, the extract at the doses of 10 and 50 mg/kg did not changed the number of crossings, rearings nor groomings. On the other hand, at the dose of 200 mg/kg it reduced the number of crossings (q = 6.25, P < 0.05) and groomings (q = 3.91, P < 0.05). When… CONTINUE READING