Central nervous system and renal vasculitis associated with primary varicella infection in a child.

@article{Caruso2001CentralNS,
  title={Central nervous system and renal vasculitis associated with primary varicella infection in a child.},
  author={J M Caruso and Glenn A. Tung and William D. Brown},
  journal={Pediatrics},
  year={2001},
  volume={107 1},
  pages={
          E9
        }
}
A 7-year-old girl with primary varicella presented with encephalopathy and focal neurologic deficits 10 days after her first skin lesions appeared. She was discovered to have bilateral wedge-shaped renal infarctions, and ischemic lesions in the conus medullaris, cerebral cortex, and deep gray matter consistent with a medium and large vessel arteritis on magnetic resonance imaging. This complication has never before been reported in an immunocompetent child with primary varicella infection, and… 
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References

SHOWING 1-10 OF 27 REFERENCES
Central nervous system manifestations of chickenpox.
A study of 57 cases of affection of the central nervous system associated with chickenpox diagnosed and treated at The Hospital for Sick Children in Toronto between 1956 and 1967, inclusive, is
Thrombotic cerebral vasculopathy associated with herpes zoster
TLDR
Evidence is provided that the vasculopathy following herpes zoster may result from direct VZV infection of the artery and the in situ thrombosis can develop within the infected vessels in the absence of clear inflammatory vasculitis.
Herpes zoster ophthalmicus with contralateral hemiplegia: identification of cause.
A patient with herpes zoster ophthalmicus developed hemiparesis that at first responded to steroids but, when these were reduced, culminated in massive cerebral infarction and death. The cause was an
Clinical features of vascular thrombosis following varicella.
TLDR
The innervation of the carotid artery and the characteristics of the varicella zoster virus itself together provide the local and systemic factors that may trigger the vasculopathy responsible for this syndrome.
The vasculopathy of varicella‐zoster virus encephalitis
Varicella‐zoster virus (VZV) encephalitis has become more prevalent in the era of acquired immunodeficiency syndrome and other immunosuppressive diseases and poses diagnostic and therapeutic
Angiographic findings in herpes zoster arteritis
TLDR
It is proposed that the pattern of angiographic abnormalities described here is characteristic of herpes zoster arteritis; furthermore, the distribution pattern of the lesions suggests that the virus may spread to these arteries via branches of the ophthalmic division of the trigeminal nerve.
Herpes zoster ophthalmicus and delayed contralateral hemiparesis caused by cerebral angiitis: Diagnosis and management approaches
Four patients with herpes zoster ophthalmicus and delayed contralateral hemiparesis are described, and their findings are compared with those in patients previously reported in the English language
Life-threatening complications of varicella.
TLDR
A substantial occurrence of life-threatening complications of varicella in childhood is demonstrated and a need for prospective epidemiologic data on the incidence of complications to determine the scope and extent ofvaricella vaccination is demonstrated.
Neurologic complications of the reactivation of varicella-zoster virus.
TLDR
The detection of varicella–zoster virus in blood vessels and other tissues by methods based on the polymerase chain reaction (PCR) has widened the recognized patterns of infection.
...
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