Central nervous stimuli increase duodenal bicarbonate secretion by release of mucosal melatonin.

@article{Sjblom2001CentralNS,
  title={Central nervous stimuli increase duodenal bicarbonate secretion by release of mucosal melatonin.},
  author={Markus Sj{\"o}blom and Gunnar Flemstr{\"o}m},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2001},
  volume={52 4 Pt 1},
  pages={671-8}
}
A number of common diseases in humans, including gastroduodenal ulcer and irritable bowel syndrome, show circadian rhythms in pain and discomfort. The neurohormone melatonin is released from enterochromaffin cells in the intestinal mucosa and from the pineal gland but its role in gastrointestinal function is largely unknown. We have studied the involvement of melatonin in stimulation of the mucosa-protective alkaline secretion by the duodenal mucosa. A 12-mm segment of proximal duodenum with an… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 12 references

Effects of melatonin on duodenal enterocyte calcium signaling and bicarbonate secretion ( abstr )

M Sjöblom, G Jedstedt, G Flemström
Gastroenterology • 2001

Gastroduodenal mucosal alkaline secretion and mucosal protection.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society • 2001

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