Central mechanisms of osmosensation and systemic osmoregulation

  title={Central mechanisms of osmosensation and systemic osmoregulation},
  author={Charles W. Bourque},
  journal={Nature Reviews Neuroscience},
Systemic osmoregulation is a vital process whereby changes in plasma osmolality, detected by osmoreceptors, modulate ingestive behaviour, sympathetic outflow and renal function to stabilize the tonicity and volume of the extracellular fluid. Furthermore, changes in the central processing of osmosensory signals are likely to affect the hydro-mineral balance and other related aspects of homeostasis, including thermoregulation and cardiovascular balance. Surprisingly little is known about how the… CONTINUE READING
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