Central mechanisms I: plasticity of central pathways.

  title={Central mechanisms I: plasticity of central pathways.},
  author={C Y Chen and Jesse P. Joad and Justin D. Bric and Ann C. Bonham},
  journal={Handbook of experimental pharmacology},
Cough is the most common symptom for which individuals seek medical attention and spend health-care dollars. Despite the burden induced by cough, the current treatments for cough are only partially effective. Delineating the sites and mechanisms in the cough central network for changes in the cough reflex could lead to new therapeutic strategies and drug target sites for more effective treatments. The first synaptic target in the CNS for the cough-related sensory input is the second-order… CONTINUE READING