Central line-associated bloodstream infection prevention

@article{Miller2012CentralLB,
  title={Central line-associated bloodstream infection prevention},
  author={Sarah E. Miller and Lisa L. Maragakis},
  journal={Current Opinion in Infectious Diseases},
  year={2012},
  volume={25},
  pages={412–422}
}
Purpose of review This review summarizes recent literature regarding the prevention of central line-associated bloodstream infection (CLABSI). Recent findings CLABSI rates in United States ICUs reported to the National Healthcare Safety Network (NHSN) have decreased dramatically in recent years. This has been achieved largely through a multifaceted approach and a focus on evidence-based best practices for central line insertion. More recent studies suggest an added benefit from implementation… 
Review of Strategies to Reduce Central Line‐Associated Bloodstream Infection (CLABSI) and Catheter‐Associated Urinary Tract Infection (CAUTI) in Adult ICUs
TLDR
A systematic search of the peer‐reviewed literature within the PubMed and Cochrane databases for interventions to reduce CLABSI and/or CAUTI in adult ICUs found interventions that addressed multiple stages within the conceptual model were common in these successful studies.
Update on infection control challenges in special pediatric populations
TLDR
Several evidence-based practices are effective in reducing the incidence and the impact of HAIs in children; however, proper implementation remains a challenge.
Minimizing central line–associated bloodstream infections in a high‐acuity liver transplant intensive care unit
Bench-to-bedside review: Challenges of diagnosis, care and prevention of central catheter-related bloodstream infections in children
TLDR
A review of the recent literature about the diagnostic and therapeutic challenges of catheter-related bloodstream infection in children and its prevention and novel molecular testing methods appear promising in overcoming some of the present diagnostic limitations of conventional blood sampling in children.
Effectiveness of antimicrobial-coated central venous catheters for preventing catheter-related blood-stream infections with the implementation of bundles: a systematic review and network meta-analysis
TLDR
Outcomes are superior for catheters impregnated with chlorhexidine/silver sulfadiazine or other antibiotics than for standard catheter in preventing CRBSIs and catheter colonization under bundles.
A Multifaceted Intervention Program to Prevent Bloodstream Infection in an IntensiveCare Unit Running Head: An Intervention for the Reductionof Bacteraemia in ICU
TLDR
An intervention program including modifying CVC insertion and maintenance as well as promoting hand hygiene seems to be an effective way of preventing BSI in intensive care units.
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References

SHOWING 1-10 OF 96 REFERENCES
Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals
TLDR
The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals in implementing and prioritizing their central line–associated bloodstream infection (CLABSI) prevention efforts.
Central Line Bundle Implementation in US Intensive Care Units and Impact on Bloodstream Infections
TLDR
In NHSN hospitals across the US, the CL Bundle is associated with lower infection rates only when compliance is high, and hospitals must target improving bundle implementation and compliance as opposed to simply instituting policies.
A Quality Improvement Initiative to Reduce Central Line–Associated Bloodstream Infections in a Neonatal Intensive Care Unit
TLDR
It is possible to reduce the rate of CLABSI, and therefore the rates of late-onset sepsis, by establishing and adhering to evidence-based guidelines, as well as other populations and areas of inpatient care.
Elimination of central-venous-catheter-related bloodstream infections from the intensive care unit
TLDR
A significant reduction in CRBSI is described for the first time in a UK ICU using a quality improvement approach and the authors believe these approaches are worthy of serious consideration elsewhere.
Prevention of Central Line–Associated Bloodstream Infections: A Journey Toward Eliminating Preventable Harm
TLDR
Comparing reductions in CLABSI rates achieved by multifaceted quality improvement efforts solely to the use of checklists to ensure adherence with appropriate infection control practices is an easily made but crucial mistake.
Eradicating Central Line–Associated Bloodstream Infections Statewide
TLDR
Hawaii demonstrated that the national program to reduce central line-associated bloodstream infections (CLABSIs) can be successfully spread, providing further evidence that most CLABSIs are preventable.
Utilizing a line maintenance team to reduce central-line-associated bloodstream infections in a neonatal intensive care unit
TLDR
A line team provided for standardized, consistent central-line maintenance care leading to a significant, sustained decrease in CLABSI in a NICU, which decreased by 65% after implementation of the line team.
Trends in central line-associated bloodstream infections in a trauma-surgical intensive care unit.
TLDR
A significant decline in the incidence of CLABSIs was reported, which reflected the national trend, and the high central line utilization ratio compared with nationally available data represents a potential target for further improvement.
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