Central hypoadrenalism.

  title={Central hypoadrenalism.},
  author={Rachel K Crowley and Nicola Argese and J W Tomlinson and P. M. Stewart},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={99 11},
CONTEXT Central hypoadrenalism is a frequent complication of pituitary and hypothalamic pathology and is associated with increased morbidity and mortality. Optimal exogenous glucocorticoid use is dependent on the use of appropriate diagnostic tests and careful assessment of the clinical response to glucocorticoid replacement therapy. EVIDENCE ACQUISITION A PubMed search for the terms central hypoadrenalism, ACTH deficiency, glucocorticoid suppression, and glucocorticoid replacement was… CONTINUE READING