Central effect of yohimbine on sexual behavior in the rat

@article{Sala1990CentralEO,
  title={Central effect of yohimbine on sexual behavior in the rat},
  author={Massimilliano Sala and Daniela Braida and Mark P. Leone and P G Calcaterra and Ettore Gori},
  journal={Physiology & Behavior},
  year={1990},
  volume={47},
  pages={165-173}
}
A large range of doses of yohimbine (Y) was administered intracerebroventricularly (ICV) (5-100 micrograms/rat) or intraperitoneally (IP) (0.35-10 mg/kg) to male rats and the effects on sexual, locomotor and general behavior were evaluated. For both routes there was a clear-cut inverted-U effect (stimulating/depressing), calculable as parabolic regressions on the log of administered doses. The maximal stimulating doses (15 micrograms/rat ICV and 1 mg/kg IP) significantly shortened mount… CONTINUE READING
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