Central cholinergic signal-mediated neuroendocrine regulation of vasopressin and oxytocin in ovine fetuses
@article{Shi2008CentralCS, title={Central cholinergic signal-mediated neuroendocrine regulation of vasopressin and oxytocin in ovine fetuses}, author={Lijun Shi and Caiping Mao and Fanxing Zeng and Yuying Zhang and Zhice Xu}, journal={BMC Developmental Biology}, year={2008}, volume={8}, pages={95 - 95} }
BackgroundThe hypothalamic-neurohypophysial system plays a fundamental role in the maintenance of body fluid homeostasis by secreting arginine vasopressin (AVP) and oxytocin (OT) in response to a variety of signals, including osmotic and nonosmotic stimuli. It is well established that central cholinergic mechanisms are critical in the regulation of cardiovascular responses and maintenance of body fluid homeostasis in adults. Our recent study demonstrated that intracerebroventricular (i.c.v…
8 Citations
Development of Oxytocin- and Vasopressin-Network in the Supraoptic and Paraventricular Nuclei of Fetal Sheep
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- 2012
This study determined the special patterns in location and distribution of oxytocinand vasopressin-neurons in the paraventricular and supraoptic nuclei from preterm to term in the ovine fetuses and demonstrated that the special distributed patterns of vasopressing network have formed in those two nuclei at least from pre term.
Development of oxytocin- and vasopressin-network in the supraoptic and paraventricular nuclei of fetal sheep.
- Biology, MedicinePhysiological research
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This study determined the special patterns in location and distribution of oxytocin- and vasopressin-neurons in the paraventricular and supraoptic nuclei from preterm to term in the ovine fetuses and provided new evidence for the structural and functional development of the oxytoc in- and Vasopress in-network before birth.
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The obtained data suggest that during FPI proteolytic enzymes participate in the formation of compensatory-adaptive reactions in the FPC, which is related to reduced vascular sensitivity of FPC during physiological pregnancy.
Gestational exposure to bisphenol A induces region-specific changes in brain metabolomic fingerprints in sheep.
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Altered urinary sodium excretion response after central cholinergic and adrenergic stimulation of adult spontaneously hypertensive rats
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These experiments provide good evidence of the existence of a central adrenergic mechanism consisting of α1 and α2-adrenoceptors which works antagonistically on regulation of renal sodium excretion and the importance of interaction of central cholinergic and/or noradrenergic receptors in the pathogenesis of spontaneous hypertension.
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