Central cholinergic signal-mediated neuroendocrine regulation of vasopressin and oxytocin in ovine fetuses

@article{Shi2008CentralCS,
  title={Central cholinergic signal-mediated neuroendocrine regulation of vasopressin and oxytocin in ovine fetuses},
  author={Lijun Shi and Caiping Mao and Fanxing Zeng and Yuying Zhang and Zhice Xu},
  journal={BMC Developmental Biology},
  year={2008},
  volume={8},
  pages={95 - 95}
}
BackgroundThe hypothalamic-neurohypophysial system plays a fundamental role in the maintenance of body fluid homeostasis by secreting arginine vasopressin (AVP) and oxytocin (OT) in response to a variety of signals, including osmotic and nonosmotic stimuli. It is well established that central cholinergic mechanisms are critical in the regulation of cardiovascular responses and maintenance of body fluid homeostasis in adults. Our recent study demonstrated that intracerebroventricular (i.c.v… 
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8 Citations
Background Citations
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Methods Citations
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8 Citations

Development of Oxytocin- and Vasopressin-Network in the Supraoptic and Paraventricular Nuclei of Fetal Sheep

This study determined the special patterns in location and distribution of oxytocinand vasopressin-neurons in the paraventricular and supraoptic nuclei from preterm to term in the ovine fetuses and demonstrated that the special distributed patterns of vasopressing network have formed in those two nuclei at least from pre term.

Development of oxytocin- and vasopressin-network in the supraoptic and paraventricular nuclei of fetal sheep.

This study determined the special patterns in location and distribution of oxytocin- and vasopressin-neurons in the paraventricular and supraoptic nuclei from preterm to term in the ovine fetuses and provided new evidence for the structural and functional development of the oxytoc in- and Vasopress in-network before birth.

Peptidase activity of the fetoplacental complex in the norm and pathology

The obtained data suggest that during FPI proteolytic enzymes participate in the formation of compensatory-adaptive reactions in the FPC, which is related to reduced vascular sensitivity of FPC during physiological pregnancy.

Gestational exposure to bisphenol A induces region-specific changes in brain metabolomic fingerprints in sheep.

Angiotensin-converting enzymes and drug discovery in cardiovascular diseases.

Oxytocin and Social Adaptation: Insights from Neuroimaging Studies of Healthy and Clinical Populations

Altered urinary sodium excretion response after central cholinergic and adrenergic stimulation of adult spontaneously hypertensive rats

These experiments provide good evidence of the existence of a central adrenergic mechanism consisting of α1 and α2-adrenoceptors which works antagonistically on regulation of renal sodium excretion and the importance of interaction of central cholinergic and/or noradrenergic receptors in the pathogenesis of spontaneous hypertension.

Development of Local RAS in Cardiovascular/Body Fluid Regulatory Systems and Hypertension in Fetal Origins

References

SHOWING 1-10 OF 61 REFERENCES

The Association of Cardiovascular Responses with Brain c-fos Expression after Central Carbachol in the Near-Term Ovine Fetus

The results indicate that the central cholinergic mechanism is functional in the control of fetal blood pressure at the last third of gestation, and the central AV3V region and hindbrain have been intact relatively during in utero development in sheep at 90% gestational stage.

Angiotensin-induced vasopressin release and activation of hypothalamic neuron in pre-term fetuses

Hypothalamic oxytocin in the developing ovine fetus: interaction with pituitary–adrenocortical function

Glucocorticoid modulation of atrial natriuretic peptide, oxytocin, vasopressin and Fos expression in response to osmotic, angiotensinergic and cholinergic stimulation

ANP as a neuroendocrine modulator of body fluid homeostasis.

That this effect is related to blockage of the activity of the brain ANPergic neurons is supported by findings in sheep and in rats that the injection of the antiserum directed against ANP into the AV3V region at least partially blocked the BVE-induced release of ANP.

Sex differences in central cholinergic and angiotensinergic control of vasopressin release.

Findings indicate that central cholinergic and angiotensinergic mechanisms controlling vasopressin release are influenced differently by gender, and the role of the gonadal steroid hormones in these mechanisms remains to be determined.

Control of release of vasopressin by neuroendocrine reflexes.

The neurones in the supraoptic and paraventricular nuclei (SON and PVN) are separate from those which secrete oxytocin and are distributed in different parts of the nuclei and suggest an excitatory, rather than inhibitory, function of the A1 noradrenergic neurones involving alpha 1-receptors.

Neuroendocrine control of body fluid metabolism.

The role played by brain ANP and its interaction with neurohypophysial hormones in the control of body fluid homeostasis is emphasized.

Central angiotensin induction of fetal brain c-fos expression and swallowing activity.

Results indicate that an ANG II-mediated central dipsogenic mechanism is intact before birth, acting at sites consistent with the dipsogenic neural network, likely contribute to fetal body fluid and amniotic fluid regulation.

Vasopressin in circulatory control and hypertension.

  • C. Johnston
  • Medicine, Biology
    Journal of hypertension
  • 1985
It seems unlikely that vasopressin acts as a direct vasoconstrictor agent in the pathogenesis of any form of experimental or human hypertension, but it may be indirectly involved through volume maintenance or interactions within the CNS.
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