Central autonomic control of the heart, angina, and pathogenic mechanisms of post-myocardial infarction depression.

@article{Horst1999CentralAC,
  title={Central autonomic control of the heart, angina, and pathogenic mechanisms of post-myocardial infarction depression.},
  author={Gert J. ter Horst},
  journal={European journal of morphology},
  year={1999},
  volume={37 4-5},
  pages={257-66}
}
Depression can develop in 20% of the patients with a myocardial infarction (MI). Pathobiological mechanisms underlying the development of mood disorders in these patients are unknown. Since post-MI depression has been associated with increased risk of mortality we hypothesized that dysfunction of limbic circuitry is part of the pathogenic processes. Both mood and cardiovascular functions are controlled by the limbic system. Here, we will review a set of experiments that support this hypothesis… CONTINUE READING

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