Central and primary visceral afferents to nucleus tractus solitarii may generate nitric oxide as a membrane-permeant neuronal messenger.

@article{Ruggiero1996CentralAP,
  title={Central and primary visceral afferents to nucleus tractus solitarii may generate nitric oxide as a membrane-permeant neuronal messenger.},
  author={David A. Ruggiero and E P Mtui and Kanao Otake and Muhammad Zubair Anwar},
  journal={The Journal of comparative neurology},
  year={1996},
  volume={364 1},
  pages={51-67}
}
An anatomical basis was sought for the postulated roles of nitric oxide (NO) as a labile transcellular messenger in the dorsal vagal complex (NTS-X). The diaphorase activity of NO synthase was used as a marker of neurons in NTS-X that are presumed to convert L-arginine to L-citrulline and NO. Nicotinamide adenine dinucleotide phosphate diaphorase (NADPHd) staining patterns in the nucleus tractus solitarii (NTS) were spatially related to terminal sites of primary visceral afferents from 1… CONTINUE READING

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