Central and peripheral mechanisms of arterial pressure lability following baroreceptor denervation.

@article{Alper1987CentralAP,
  title={Central and peripheral mechanisms of arterial pressure lability following baroreceptor denervation.},
  author={Richard H Alper and H J Jacob and Michael J. Brody},
  journal={Canadian journal of physiology and pharmacology},
  year={1987},
  volume={65 8},
  pages={1615-8}
}
Deafferentation of sinoaortic baroreceptors produces a marked increase in the lability of arterial pressure that is sustained chronically. Studies reviewed in this paper were designed to determine the mechanisms responsible for generating arterial pressure lability. Pharmacological interruption of the humoral vasopressin and angiotensin systems failed to alter arterial pressure lability. In contrast, blockade of sympathetic nervous system transmission at both ganglionic and alpha-adrenergic… CONTINUE READING

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