Central and peripheral hypersensitivity in the irritable bowel syndrome.

  title={Central and peripheral hypersensitivity in the irritable bowel syndrome.},
  author={QiQi Zhou and Roger B. Fillingim and Joseph L. Riley and William B. Malarkey and G. Nicholas Verne},
  volume={148 3},
Previous investigations of somatic hypersensitivity in IBS patients have typically involved only a single stimulus modality, and little information exists regarding whether patterns of somatic pain perception vary across stimulus modalities within a group of patients with IBS. Therefore, the current study was designed to characterize differences in perceptual responses to a battery of noxious somatic stimuli in IBS patients compared to controls. A total of 78 diarrhea-predominant and 57… CONTINUE READING
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