Central and peripheral circadian clocks in mammals.

  title={Central and peripheral circadian clocks in mammals.},
  author={Jennifer A Mohawk and Carla B. Green and Joseph S Takahashi},
  journal={Annual review of neuroscience},
The circadian system of mammals is composed of a hierarchy of oscillators that function at the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell-autonomous circadian oscillator throughout the body, yet this clock system is adapted to different functional contexts. In the central suprachiasmatic nucleus (SCN) of the hypothalamus, a coupled population of neuronal circadian oscillators acts as a master pacemaker for the organism to drive rhythms in activity and… CONTINUE READING
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