Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in rats

To explore the site of action of maprotiline, as an atypical antidepressant, on carrageenan-induced paw edema. Male Wistar rats were used. Firstly, the anti-inflammatory effect of systemic maprotiline (12.5, 25 and 50 mg kg−1) was assessed using a paw edema model. Secondly, different doses of maprotiline were administrated intracerebroventricularly… CONTINUE READING

7 Figures & Tables

Topics

Statistics

02040201020112012201320142015201620172018
Citations per Year

65 Citations

Semantic Scholar estimates that this publication has 65 citations based on the available data.

See our FAQ for additional information.